Title	The MHC class II associated invariant chain limits the immunogenicity of genetically modified human tumor cell vaccines
Author	Thompson, James Andrew
Advisors	Ostrand-Rosenberg, Suzanne
Program	Biological Sciences
UMBC Department	Biological Sciences
Document Type	dissertation
Sponsors	University of Maryland, Baltimore County (UMBC)
Keywords	Cancer; vaccine; Class II Major Histocompatibility Complex; MHC II; invariant chain; RNAi; Health Sciences, Immunology (0982); Health Sciences, Oncology (0992); Biology, Molecular (0307)
Date Issued	2008-02-05; *
Abstract	Activation of tumor-reactive T lymphocytes is a promising approach for the treatment of patients with metastatic cancers. CD8<sup>+
Format	application:pdf
Language	en
Collection	UMBC Theses and Dissertations
Rights Statement	This item may be protected under Title 17 of the U.S. Copyright Law. It is made available by UMBC for non-commercial research and education. For permission to publish or reproduce, please see http://aok.lib.umbc.edu/specoll/repro.php or contact Special Collections at speccoll(at)umbc.edu.

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The MHC class II associated invariant chain limits the immunogenicity of genetically modified human tumor cell vaccines